Modulation of the Nitrergic Pathway via Activation of PPAR-γ Contributes to the Neuroprotective Effect of Pioglitazone Against Streptozotocin-Induced Memory Dysfunction

Alzheimer’s disease (AD) is a neurodegenerative disease characterized by impaired memory function and oxidative damage. NO is a major signaling molecule produced in the central nervous system to modulate neurological activity through modulating nitric oxide synthase. Recently, PPAR-γ agonists have s...

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Bibliographic Details
Published in:Journal of Molecular Neuroscience
Main Author: Prakash A.; Kumar A.; Ming L.C.; Mani V.; Majeed A.B.A.
Format: Article
Language:English
Published: Springer New York LLC 2015
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84931571095&doi=10.1007%2fs12031-015-0508-7&partnerID=40&md5=a0ff0b7cf5ef70e8b8e7fc31b1421e69