Diastereoselective reduction of 2,3-dioxo-4-carboxy-5-substituted pyrrolidines using NaBH4/AcOH and heterogenous hydrogenation reactions

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Diastereoselective reduction of 2,3-dioxo-4-carboxy-5-substituted pyrrolidines using NaBH4/AcOH and heterogenous hydrogenation reactions

Diastereoselective reduction of 2,3-dioxo-4-carboxy-5-(substituted)pyrrolidine 1 by NaBH4/AcOH and heterogenous hydrogenation were reported. Stereochemical assignment and diastereomeric ratios of the products were determined using 1H NMR and single crystal X-ray analyses. The steric factors of the C...

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Bibliographic Details
Published in:	Journal of the Korean Chemical Society
Main Author:	Mohammat M.F.; Mansor N.S.; Shaameri Z.; Hamzah A.S.
Format:	Article
Language:	English
Published:	Korean Chemical Society 2015
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-84921871900&doi=10.5012%2fjkcs.2015.59.1.31&partnerID=40&md5=19fd4f6f9213ba6b5f78ba0f5b0e8e7b

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