Design and synthesis of chalcone derivatives as potent tyrosinase inhibitors and their structural activity relationship
Browning of fruits and vegetables is a serious issue in the food industry, as it damages the organoleptic properties of the final products. Overproduction of melanin causes aesthetic problems such as melisma, freckles and lentigo. In this study, a series of chalcones (1-10) have been synthesized and...
Published in: | Journal of Molecular Structure |
---|---|
Main Author: | Akhtar M.N.; Sakeh N.M.; Zareen S.; Gul S.; Lo K.M.; Ul-Haq Z.; Shah S.A.A.; Ahmad S. |
Format: | Article |
Language: | English |
Published: |
Elsevier
2015
|
Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84921298964&doi=10.1016%2fj.molstruc.2014.12.073&partnerID=40&md5=11999790af751f9d6af868663fb4005c |
Similar Items
-
Synthesis and structure-activity relationship of thiobarbituric acid derivatives as potent inhibitors of urease
by: Khan K.M.; Rahim F.; Khan A.; Shabeer M.; Hussain S.; Rehman W.; Taha M.; Khan M.; Perveen S.; Choudhary M.I.
Published: (2014) -
Synthesis, biological evaluation and molecular docking study of oxindole based chalcone analogues as potent anti-Alzheimer agents
by: Taha M.; Sadia H.; Rahim F.; Khan M.I.; Hayat S.; Iqbal N.; Nawaz F.; Ullah H.; Zada H.; Shah S.A.A.; Wadood A.; Farooq R.K.; Khan K.M.
Published: (2023) -
Exploring diabetics II inhibitors based on benzodioxin derivatives, structure activity relationship, molecular docking and ADME property study
by: Al-Abdulbaqi M.A.; Taha M.; Rahim F.; Uddin I.; Uddin N.; Wadood A.; Haq S.; Iqbal N.; Khan K.M.; Ali shah S.A.; Ali M.
Published: (2024) -
Design, synthesis and computational studies of N-(substituted-phenyl)-4-(4-phenyl-1-piperazinyl)butanamides as potent anti-melanogenic and tyrosinase inhibitors
by: Raza H.; Abbasi M.A.; Rehman A.-U.; Siddiqui S.Z.; Hassan M.; Shah S.A.A.; Shahid M.; Hong H.; Seo S.-Y.
Published: (2020) -
Experimental and computational profiling of novel bis-Schiff base derivatives bearing α-naphthalene moiety as potential tyrosinase inhibitors
by: Shah T.A.; Alam A.; Zainab; Khan M.; Elhenawy A.A.; Ayaz M.; Ali M.; Latif A.; Shah S.A.A.; Ahmad M.
Published: (2025)