Design and synthesis of chalcone derivatives as potent tyrosinase inhibitors and their structural activity relationship

Browning of fruits and vegetables is a serious issue in the food industry, as it damages the organoleptic properties of the final products. Overproduction of melanin causes aesthetic problems such as melisma, freckles and lentigo. In this study, a series of chalcones (1-10) have been synthesized and...

Full description

Bibliographic Details
Published in:Journal of Molecular Structure
Main Author: Akhtar M.N.; Sakeh N.M.; Zareen S.; Gul S.; Lo K.M.; Ul-Haq Z.; Shah S.A.A.; Ahmad S.
Format: Article
Language:English
Published: Elsevier 2015
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84921298964&doi=10.1016%2fj.molstruc.2014.12.073&partnerID=40&md5=11999790af751f9d6af868663fb4005c