Bis(indolyl)methanes synthesis through sodium iodate and sodium hydrogen sulfite in water
An effective and eco-friendly method for the bis(indolyl)methanes synthesis has been developed. A successive methodology involving sodium iodate/sodium hydrogen sulfite catalyzed reaction of indole with many aldehydes gave the resultant bis-indol in good yield. This method offers synthetically inexp...
Published in: | Journal of the Chemical Society of Pakistan |
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Language: | English |
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Chemical Society of Pakistan
2015
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Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84920925932&partnerID=40&md5=ee98e21add15e44622aca39fdf0fd301 |
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2-s2.0-84920925932 Khan K.M.; Rahim F.; Shah S.A.A.; Taha M.; Ismail N.H.; Manzoor M.; Miana G.A.; Perveen S. Bis(indolyl)methanes synthesis through sodium iodate and sodium hydrogen sulfite in water 2015 Journal of the Chemical Society of Pakistan 36 6 https://www.scopus.com/inward/record.uri?eid=2-s2.0-84920925932&partnerID=40&md5=ee98e21add15e44622aca39fdf0fd301 An effective and eco-friendly method for the bis(indolyl)methanes synthesis has been developed. A successive methodology involving sodium iodate/sodium hydrogen sulfite catalyzed reaction of indole with many aldehydes gave the resultant bis-indol in good yield. This method offers synthetically inexpensive alternate to the previously developed procedures for the bis-indol synthesis. The use of a low-cost and straightforwardly accessible catalyst, improved yields and a simple reaction process are the salient features of the current method. Chemical Society of Pakistan 2535106 English Article |
author |
Khan K.M.; Rahim F.; Shah S.A.A.; Taha M.; Ismail N.H.; Manzoor M.; Miana G.A.; Perveen S. |
spellingShingle |
Khan K.M.; Rahim F.; Shah S.A.A.; Taha M.; Ismail N.H.; Manzoor M.; Miana G.A.; Perveen S. Bis(indolyl)methanes synthesis through sodium iodate and sodium hydrogen sulfite in water |
author_facet |
Khan K.M.; Rahim F.; Shah S.A.A.; Taha M.; Ismail N.H.; Manzoor M.; Miana G.A.; Perveen S. |
author_sort |
Khan K.M.; Rahim F.; Shah S.A.A.; Taha M.; Ismail N.H.; Manzoor M.; Miana G.A.; Perveen S. |
title |
Bis(indolyl)methanes synthesis through sodium iodate and sodium hydrogen sulfite in water |
title_short |
Bis(indolyl)methanes synthesis through sodium iodate and sodium hydrogen sulfite in water |
title_full |
Bis(indolyl)methanes synthesis through sodium iodate and sodium hydrogen sulfite in water |
title_fullStr |
Bis(indolyl)methanes synthesis through sodium iodate and sodium hydrogen sulfite in water |
title_full_unstemmed |
Bis(indolyl)methanes synthesis through sodium iodate and sodium hydrogen sulfite in water |
title_sort |
Bis(indolyl)methanes synthesis through sodium iodate and sodium hydrogen sulfite in water |
publishDate |
2015 |
container_title |
Journal of the Chemical Society of Pakistan |
container_volume |
36 |
container_issue |
6 |
doi_str_mv |
|
url |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84920925932&partnerID=40&md5=ee98e21add15e44622aca39fdf0fd301 |
description |
An effective and eco-friendly method for the bis(indolyl)methanes synthesis has been developed. A successive methodology involving sodium iodate/sodium hydrogen sulfite catalyzed reaction of indole with many aldehydes gave the resultant bis-indol in good yield. This method offers synthetically inexpensive alternate to the previously developed procedures for the bis-indol synthesis. The use of a low-cost and straightforwardly accessible catalyst, improved yields and a simple reaction process are the salient features of the current method. |
publisher |
Chemical Society of Pakistan |
issn |
2535106 |
language |
English |
format |
Article |
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record_format |
scopus |
collection |
Scopus |
_version_ |
1809678486789423104 |