Synthesis of novel inhibitors of α-glucosidase based on the benzothiazole skeleton containing benzohydrazide moiety and their molecular docking studies

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Synthesis of novel inhibitors of α-glucosidase based on the benzothiazole skeleton containing benzohydrazide moiety and their molecular docking studies

In an effort to design and synthesize a new class of α-glucosidase inhibitor, we synthesized benzothiazole hybrid having benzohydrazide moiety (5). Compound 5 was reacted with various substituted aryl aldehyde to generate a small library of compounds 6-35. Synthesis of compounds was confirmed by the...

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Bibliographic Details
Published in:	European Journal of Medicinal Chemistry
Main Author:	Taha M.; Ismail N.H.; Lalani S.; Fatmi M.Q.; Atia-Tul-Wahab; Siddiqui S.; Khan K.M.; Imran S.; Choudhary M.I.
Format:	Article
Language:	English
Published:	Elsevier Masson SAS 2015
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-84920848432&doi=10.1016%2fj.ejmech.2015.01.009&partnerID=40&md5=43b5ed99e419a1ce3031e5c687a043b1

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