Synthesis of novel inhibitors of α-glucosidase based on the benzothiazole skeleton containing benzohydrazide moiety and their molecular docking studies
In an effort to design and synthesize a new class of α-glucosidase inhibitor, we synthesized benzothiazole hybrid having benzohydrazide moiety (5). Compound 5 was reacted with various substituted aryl aldehyde to generate a small library of compounds 6-35. Synthesis of compounds was confirmed by the...
| Published in: | European Journal of Medicinal Chemistry |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier Masson SAS
2015
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84920848432&doi=10.1016%2fj.ejmech.2015.01.009&partnerID=40&md5=43b5ed99e419a1ce3031e5c687a043b1 |