Establishing and managing a periodontal biobank for research: The sharing of experience

• Published in: Oral Diseases
• Main Author: Vaithilingam R.D.; Safii S.H.; Baharuddin N.A.; Karen-Ng L.P.; Saub R.; Ariffin F.; Ramli H.; Sharifuddin A.; Hidayat M.F.H.; Raman R.; Chan Y.K.; Rani N.A.; Rahim R.A; Shahruddin N.; Cheong S.C.; Bartold P.M.; Zain R.B.
• Format: Review
• Language: English
• Published: Blackwell Publishing Ltd 2015
• Online Access: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84919442109&doi=10.1111%2fodi.12267&partnerID=40&md5=f7c8090487076ca50812503ec7cd2ac7

Periodontal bio-repositories, which allow banking of clinically validated human data and biological samples, provide an opportunity to derive biomarkers for periodontal diagnosis, prognosis and therapeutic activities which are expected to improve patient management. This article presents the establishing of the Malaysian Periodontal Database and Biobank System (MPDBS) which was initiated in 2011 with the aim to facilitate periodontal research. Partnerships were established with collaborating centres. Policies on specimen access, authorship and acknowledgement policies were agreed upon by all participating centres before the initiation of the periodontal biobank. Ethical approval for the collection of samples and data were obtained from institutional ethics review boards. A broad-based approach for informed consent was used, which covered areas related to quality of life impacts, genetics and molecular aspects of periodontal disease. Sample collection and processing was performed using a standardized protocol. Biobanking resources such as equipment and freezers were shared with the Malaysian Oral Cancer Database and Tissue Bank System (MOCDTBS). In the development of the MPDBS, challenges that were previously faced by the MOCDTBS were considered. Future challenges in terms of ethical and legal issues will be faced when international collaborations necessitate the transportation of specimens across borders. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.