Mechanisms of α-Mangostin-Induced Antinociception in a Rodent Model

QR Code

Mechanisms of α-Mangostin-Induced Antinociception in a Rodent Model

Objective: Elucidate the antinociceptive mechanisms of α-mangostin isolated from Garcinia malaccensis Linn. Methods: Male mice/rats (n = 6/group) were used in this between-group study. To determine α-mangostin's antinociceptive profile, animals were given α-mangostin orally (3, 30, or 100 mg/kg...

Full description

Bibliographic Details
Published in:	Biological Research for Nursing
Main Author:	Mohd. Sani M.H.; Taher M.; Susanti D.; Kek T.L.; Salleh M.Z.; Zakaria Z.A.
Format:	Article
Language:	English
Published:	SAGE Publications Inc. 2015
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-84919432458&doi=10.1177%2f1099800414529648&partnerID=40&md5=cdfae79d7e3d41198210c868cab3189e

Similar Items

Antinociceptive activity of methanolic extract of Muntingia calabura leaves: Further elucidation of the possible mechanisms
by: Zakaria Z.A.; Sani M.H.M.; Cheema M.S.; Kader A.A.; Kek T.L.; Salleh M.Z.
Published: (2014)

Antinociception of petroleum ether fraction derived from crude methanol extract of Melastoma malabathricum leaves and its possible mechanisms of action in animal models
by: Zakaria Z.A.; Jaios E.S.; Omar M.H.; Abd. Rahman S.; Hamid S.S.A.; Ching S.M.; Teh L.K.; Salleh M.Z.; Deny S.; Taher M.
Published: (2016)

Antinociceptive Activity of Methanolic Extract of Clinacanthus nutans Leaves: Possible Mechanisms of Action Involved
by: Zakaria Z.A.; Abdul Rahim M.H.; Roosli R.A.J.; Mohd Sani M.H.; Omar M.H.; Tohid S.F.; Othman F.; Ching S.M.; Abdul Kadir A.
Published: (2018)

Mechanisms of gastroprotection of methanol extract of Melastoma malabathricum leaves
by: Zakaria Z.A.; Balan T.; Mamat S.S.; Mohtarrudin N.; Kek T.L.; Salleh M.Z.
Published: (2015)

Possible mechanisms of antinociception of methanol extract of Melastoma malabathricum leaves
by: Jaios E.S.; Rahman S.; Ching S.M.; Kadir A.A.; Desa M.N.M.; Zakaria Z.A.
Published: (2016)

Antinociceptive Activity of Petroleum Ether Fraction of Clinacanthus nutans Leaves Methanolic Extract: Roles of Nonopioid Pain Modulatory Systems and Potassium Channels
by: Zakaria Z.A.; Abdul Rahim M.H.; Roosli R.A.J.; Mohd Sani M.H.; Marmaya N.H.; Omar M.H.; Teh L.K.; Salleh M.Z.
Published: (2019)

Effect of methanol extract of Dicranopteris linearis against carbon tetrachloride- induced acute liver injury in rats
by: Kamisan F.H.; Yahya F.; Mamat S.S.; Kamarolzaman M.F.F.; Mohtarrudin N.; Kek T.L.; Salleh M.Z.; Hussain M.K.; Zakaria Z.A.
Published: (2014)

In vivo antinociceptive and anti-inflammatory activities of dried and fermented processed virgin coconut oil
by: Zakaria Z.A.; Somchit M.N.; Mat Jais A.M.; Teh L.K.; Salleh M.Z.; Long K.
Published: (2011)

Hepatoprotective action of various partitions of methanol extract of Bauhinia purpurea leaves against paracetamol-induced liver toxicity: Involvement of the antioxidant mechanisms
by: Zakaria Z.A.; Yahya F.; Mamat S.S.; Mahmood N.D.; Mohtarrudin N.; Taher M.; Hamid S.S.A.; Teh L.K.; Salleh M.Z.
Published: (2016)

Preliminary analysis of the antinociceptive activity of zerumbone
by: Sulaiman M.R.; Perimal E.K.; Zakaria Z.A.; Mokhtar F.; Akhtar M.N.; Lajis N.H.; Israf D.A.
Published: (2009)

Methanolic extract of clinacanthus nutans exerts antinociceptive activity via the opioid/nitric oxide-mediated, but cGMP-independent, pathways
by: Abdul Rahim M.H.; Zakaria Z.A.; Mohd Sani M.H.; Omar M.H.; Yakob Y.; Cheema M.S.; Ching S.M.; Ahmad Z.; Abdul Kadir A.
Published: (2016)

The Mechanism of Anxiolytic Effects of Moringa oleifera Leaf Extracts Associated with Significant Differential Expression of Crhb, Faah2a, Mao, and Pah Genes in Danio rerio
by: Najmi M.F.; Rofiee M.S.; Kek T.L.; Yusof F.Z.M.; Salleh M.Z.
Published: (2023)

ALPHA-MANGOSTIN (Garcinia mangostana Linn.) AND ITS POTENTIAL APPLICATION IN MITIGATING CHRONIC WOUND HEALING
by: Patrick M.; Zohdi W.N.W.M.; Muid S.A.; Omar E.
Published: (2022)

Antinociceptive activity of petroleum ether fraction obtained from methanolic extract of Clinacanthus nutans leaves involves the activation of opioid receptors and NO-mediated/cGMP-independent pathway
by: Zakaria Z.A.; Abdul Rahim M.H.; Mohd Sani M.H.; Omar M.H.; Ching S.M.; Abdul Kadir A.; Ahmed Q.U.
Published: (2019)

Evaluation of hypoglycemic activity and toxicity profiles of the leaves of ficus deltoidea in rodents
by: Ilyanie Y.; Wong T.W.; Choo C.Y.
Published: (2011)

Pharmacogenomics based practice in Malaysia: The attitude, knowledge and adoption by the healthcare professionals
by: Bannur Z.; Bahaman S.; Salleh M.Z.; Kek T.L.
Published: (2014)

Home Range and Macrohabitat Usage of the Important Rodent Reservoirs of Leptospira in Selangor, Malaysia
by: Yusof M.A.; Mohd-Taib F.S.; Ishak S.N.; Md-Nor S.; Md-Sah S.A.
Published: (2024)

Home range and macrohabitat usage of the important rodent reservoirs of Leptospira in Selangor, Malaysia
by: Yusof, et al.
Published: (2024)

Pharmacological properties of Centella asiatica hydrogel in accelerating wound healing in rabbits
by: Sh Ahmed A.; Taher M.; Mandal U.K.; Jaffri J.M.; Susanti D.; Mahmood S.; Zakaria Z.A.
Published: (2019)

Hepatoprotective activity of methanolic extract of bauhinia purpurea leaves against paracetamol-induced hepatic damage in rats
by: Yahya F.; Mamat S.S.; Kamarolzaman M.F.F.; Seyedan A.A.; Jakius K.F.; Mahmood N.D.; Shahril M.S.; Suhaili Z.; Mohtarrudin N.; Susanti D.; Somchit M.N.; Teh L.K.; Salleh M.Z.; Zakaria Z.A.
Published: (2013)

Pressure-induced enhancement of mechanical performance in ZrC system
by: Yong Y.S.; Chang Y.H.R.; Low L.C.; Lim T.L.; Yoon T.L.
Published: (2022)

Enhanced adsorption and biocompatibility of polysulfone hollow fibre membrane via the addition of silica/alpha-mangostin hybrid nanoparticle for uremic toxins removal
by: Mansur S.; Othman M.H.D.; Abidin M.N.Z.; Ismail A.F.; Abdul Kadir S.H.S.; Goh P.S.; Hasbullah H.; Ng B.C.; Abdullah M.S.; Mustafar R.
Published: (2021)

Methanol extract of Muntingia calabura leaves attenuates CCl4-induced liver injury: possible synergistic action of flavonoids and volatile bioactive compounds on endogenous defence system
by: Zakaria Z.A.; Mahmood N.D.; Omar M.H.; Taher M.; Basir R.
Published: (2019)

Antinociceptive, anti-inflammatory, and antipyretic properties of an aqueous extract of Dicranopteris linearis leaves in experimental animal models
by: Zakaria Z.A.; Abdul Ghani Z.D.F.; Raden Mohd. Nor R.N.S.; Gopalan H.K.; Sulaiman M.R.; Mat Jais A.M.; Somchit M.N.; Kader A.A.; Ripin J.
Published: (2008)

Nodamura virus B2 amino terminal domain sensitivity to small interfering RNA
by: Shaik Syed Ali P.; John J.; Selvaraj M.; Kek T.L.; Salleh M.Z.
Published: (2015)

Antioxidant, anti-inflammatory and antinociceptive activities of Mitragyna speciosa and Erythroxylum cuneatum
by: Saleh S.R.; Hasan M.H.; Said M.I.M.; Adenan M.I.; Adam A.
Published: (2012)

Metabolite Biomarkers and Predictive Model Analysis for Patients with Type 2 Diabetes Mellitus With and Without Complications
by: Kek T.L.; Rofiee M.S.; Ghani R.A.; Nor N.A.M.; Salleh M.Z.
Published: (2023)

Virtual screening, ADME study, and molecular dynamic simulation of chalcone and flavone derivatives as 5-Lipoxygenase (5-LO) inhibitor
by: Mohd Amin S.N.; Md Idris M.H.; Selvaraj M.; Mohd Amin S.N.; Jamari H.; Kek T.L.; Salleh M.Z.
Published: (2020)

Method development and validation for quantification of cortisol and cortisone using ultra-high performance liquid chromatography-tandem mass spectrometry; [Pembangunan dan pengesahan kaedah untuk kuantifikasi kortisol dan kortison menggunakan kromatografi cecair berprestasi ultra tinggi-spektrometri jisim gabungan]
by: Hazirah A.A.; Rofiee M.S.; Jam M.Z.J.; Jamari M.H.; Janor R.M.; James R.J.; Kek T.L.; Salleh M.Z.
Published: (2019)

Environmental enrichment improves cognitive function, learning, memory and anxiety-related behaviours in rodent models of dementia: Implications for future study
by: Mohd Sahini S.N.; Mohd Nor Hazalin N.A.; Srikumar B.N.; Jayasingh Chellammal H.S.; Surindar Singh G.K.
Published: (2024)

Environmental enrichment improves cognitive function, learning, memory and anxiety-related behaviours in rodent models of dementia: Implications for future study
by: Sahini, et al.
Published: (2024)

Analysis of expression of vitamin E-binding proteins in H2O2induced SK-N-SH neuronal cells supplemented with α-tocopherol and tocotrienol-rich fraction
by: Chiroma A.A.; Khaza'ai H.; Hamid R.A.; Chang S.K.; Zakaria Z.A.; Zainal Z.
Published: (2020)

Tocotrienols and α-tocopherol reduced acute and chronic lung lipid peroxidation induced by paraquat in rats
by: Asmadi A.Y.; Adam A.; Wan Ngah W.Z.; Norazlina M.; Kamisah Y.; Nur-Azlina M.F.; Qodriyah M.S.; Ahmad N.S.; Gapor M.T.; Marzuki A.
Published: (2005)

THE EFFECTS OF GENETIC VARIANTS TOWARDS WEIGHT AND BIOCHEMICAL CHANGES IN WEIGHT MANAGEMENT PROGRAM
by: Mohd Asmawi U.M.; Abdul Halim N.I.H.; Mohidin S.A.A.; Rajab N.; Kek T.L.; Salleh M.Z.; Mansyur M.; Md Nor N.
Published: (2023)

The implication of the polymorphisms of COX-1, UGT1A6, and CYP2C9 among cardiovascular disease patients treated with aspirin
by: Abdul Jalil N.J.; Bannur Z.; Derahman A.; Maskon O.; Darinah N.; Hamidi H.; Ali O.; Gunasekaran; Rafizi M.; Azreen N.I.; Kek T.L.; Salleh M.Z.
Published: (2015)

Solvent-induced morphological formation, optical and photoelectrochemical performance of α-Fe2O3 photoanode
by: Aadenan A.; Arzaee N.A.; Noh M.F.M.; Mumthas I.N.N.; Daud M.N.M.; Mohamed N.A.; Teridi M.A.M.
Published: (2022)

Severe hyperthermia induces apoptosis mediated by caspases activation and suppression of Hsp90α expression in osteosarcoma cells
by: Nashiry M.A.; Froemming G.R.A.; Keong Y.S.; Ismail A.B.M.; Din A.M.; Al-Khateeb A.M.
Published: (2019)

Targeting signaling pathways with andrographolide in cancer therapy (Review)
by: Shaharudin N.S.; Singh G.K.S.; Kek T.L.; Sultan S.
Published: (2024)

Mechanism(s) of action underlying the gastroprotective effect of ethyl acetate fraction obtained from the crude methanolic leaves extract of Muntingia calabura
by: Zakaria Z.A.; Balan T.; Azemi A.K.; Omar M.H.; Mohtarrudin N.; Ahmad Z.; Abdullah M.N.H.; Desa M.N.M.; Teh L.K.; Salleh M.Z.
Published: (2016)

Evaluation and docking of indole sulfonamide as a potent inhibitor of α-glucosidase enzyme in streptozotocin –induced diabetic albino wistar rats
by: Taha M.; Imran S.; Salahuddin M.; Iqbal N.; Rahim F.; Uddin N.; Shehzad A.; Khalid Farooq R.; Alomari M.; Mohammed Khan K.
Published: (2021)