Mitochondrial targeting of bilirubin regulatory enzymes: An adaptive response to oxidative stress
The intracellular level of bilirubin (BR), an endogenous antioxidant that is cytotoxic at high concentrations, is tightly controlled within the optimal therapeutic range. We have recently described a concerted intracellular BR regulation by two microsomal enzymes: heme oxygenase 1 (HMOX1), essential...
Published in: | Toxicology and Applied Pharmacology |
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Main Author: | |
Format: | Article |
Language: | English |
Published: |
Academic Press Inc.
2015
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Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84916887437&doi=10.1016%2fj.taap.2014.11.010&partnerID=40&md5=eb0327cd75cbd5c4287709b1864b63ea |