Mitochondrial targeting of bilirubin regulatory enzymes: An adaptive response to oxidative stress

The intracellular level of bilirubin (BR), an endogenous antioxidant that is cytotoxic at high concentrations, is tightly controlled within the optimal therapeutic range. We have recently described a concerted intracellular BR regulation by two microsomal enzymes: heme oxygenase 1 (HMOX1), essential...

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Bibliographic Details
Published in:Toxicology and Applied Pharmacology
Main Author: Muhsain S.N.F.; Lang M.A.; Abu-Bakar A.
Format: Article
Language:English
Published: Academic Press Inc. 2015
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84916887437&doi=10.1016%2fj.taap.2014.11.010&partnerID=40&md5=eb0327cd75cbd5c4287709b1864b63ea