ACE2 activation by xanthenone prevents leptin-induced increases in blood pressure and proteinuria during pregnancy in Sprague-Dawley rats

This study investigates the effect of ACE2 activation on leptin-induced changes in systolic blood pressure (SBP), proteinuria, endothelial activation and ACE2 expression during pregnancy in Sprague-Dawley rats. Pregnant rats were given subcutaneous injection of either saline, or leptin, or leptin pl...

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Bibliographic Details
Published in:Reproductive Toxicology
Main Author: Ibrahim H.S.; Froemming G.R.A.; Omar E.; Singh H.J.
Format: Article
Language:English
Published: Elsevier Inc. 2014
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84907553885&doi=10.1016%2fj.reprotox.2014.08.006&partnerID=40&md5=0b0a636c34dec04e5bcc0ef979d9fcd5

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