Phenoxyacetohydrazide schiff bases: β-glucuronidase inhibitors
Phenoxyacetohydrazide Schiff base analogs 1-28 have been synthesized and their in vitro β-glucouoronidase inhibition potential studied. Compounds 1 (IC50 = 9.20 ± 0.32 μM), 5 (IC50= 9.47 ± 0.16 μM), 7 (IC50 = 14.7 ± 0.19 μM), 8 (IC50 = 15.4 ± 1.56 μM), 11 (IC50 = 19.6 ± 0.62 μM), 12 (IC50 = 30.7 ± 1...
| Published in: | Molecules |
|---|---|
| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2014
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84904816945&doi=10.3390%2fmolecules19078788&partnerID=40&md5=4ea215c3b1b56d6b5540b58789414447 |