Wound healing analysis of pectin/carboxymethyl cellulose/microfibrillated cellulose based composite scaffolds

In our previous study, we have synthesised pectin/carboxymethyl cellulose/microfibrillated cellulose composite scaffolds by lyophilisation and investigated its morphological, mechanical, thermal properties and tested their cytotoxicity. In this work, we explored the wound healing ability of pectin/c...

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書目詳細資料
發表在:Materials Letters
主要作者: Ninan N.; Muthiah M.; Park I.-K.; Kalarikkal N.; Elain A.; Wui Wong T.; Thomas S.; Grohens Y.
格式: Article
語言:English
出版: Elsevier 2014
在線閱讀:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84903640058&doi=10.1016%2fj.matlet.2014.06.056&partnerID=40&md5=2d5f836605152e7f1a1f5a56920e7c0c
實物特徵
總結:In our previous study, we have synthesised pectin/carboxymethyl cellulose/microfibrillated cellulose composite scaffolds by lyophilisation and investigated its morphological, mechanical, thermal properties and tested their cytotoxicity. In this work, we explored the wound healing ability of pectin/carboxymethyl cellulose/microfibrillated cellulose based composite scaffolds. The pore size of the prepared scaffold was ideal for the growth of dermal fibroblasts. The in vivo studies conducted on Sprague Dawley rats showed that it could promote skin regeneration within ten days. The histological examination revealed excellent collagen deposition and complete re-epithelialisation in case of rats treated with composite, confirming its potential as excellent wound dressing material. © 2014 Elsevier B.V.
ISSN:0167577X
DOI:10.1016/j.matlet.2014.06.056