Profiles of inflammatory markers for Traumatised and nontraumatised incisors during orthodontic treatment with two archwire changes

Orthodontic treatment may cause dental root resorption. The risk of dental root resorption increases in orthodontic treated-traumatised teeth. An approach to monitor root resorption is by monitoring inflammatory markers. Therefore, we observed the profiles of inflammatory markers namely Creatine Kin...

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Published in:Journal of Biological Sciences
Main Author: Yamamoto Z.; Jaafar I.M.; Wahab R.M.A.; Ariffin Z.Z.; Abidin I.Z.Z.; Senafi S.; Ariffin S.H.Z.
Format: Article
Language:English
Published: Asian Network for Scientific Information 2014
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84896449345&doi=10.3923%2fjbs.2014.299.304&partnerID=40&md5=e9503d31448685c0052889eb0fda8a57
id 2-s2.0-84896449345
spelling 2-s2.0-84896449345
Yamamoto Z.; Jaafar I.M.; Wahab R.M.A.; Ariffin Z.Z.; Abidin I.Z.Z.; Senafi S.; Ariffin S.H.Z.
Profiles of inflammatory markers for Traumatised and nontraumatised incisors during orthodontic treatment with two archwire changes
2014
Journal of Biological Sciences
14
4
10.3923/jbs.2014.299.304
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84896449345&doi=10.3923%2fjbs.2014.299.304&partnerID=40&md5=e9503d31448685c0052889eb0fda8a57
Orthodontic treatment may cause dental root resorption. The risk of dental root resorption increases in orthodontic treated-traumatised teeth. An approach to monitor root resorption is by monitoring inflammatory markers. Therefore, we observed the profiles of inflammatory markers namely Creatine Kinase (CK), nitric oxide (NO), lactate dehydrogenase (LDH) and aspartate aminotransferase (AST) to determine their importance in orthodontic treatment especially in traumatised and nontraumatised incisors. A total of 13 subjects (7 female, 6 male) participated in this study. Samples were collected from gingival crevicular fluid at baseline (M0), 2 weeks after 0.014 NiTi archwire (Ml) and 2 weeks after 0.018 NiTi archwire (M2). All enzyme activities were measured spectrophotometrically at 340 nm. Griess assay was used to measure nitric oxide level. The NO concentration and activities of CK, LDH and AST were not significantly different between traumatised and nontraumatised incisors groups during observation period (p>0.05). Compared to Ml, NO concentration decreased significantly in M2. Other comparisons of all four markers over period of archwire changes in both traumatised and nontraumatised incisors groups showed no significant differences. Inflammatory markers showed different activities or level as responses to previous archwire usage and archwire changes. All markers are not sensitive enough to be categorized as inflammatory markers during orthodontic treatment with two archwire changes. © 2014 Asian Network for Scientific Information.
Asian Network for Scientific Information
17273048
English
Article

author Yamamoto Z.; Jaafar I.M.; Wahab R.M.A.; Ariffin Z.Z.; Abidin I.Z.Z.; Senafi S.; Ariffin S.H.Z.
spellingShingle Yamamoto Z.; Jaafar I.M.; Wahab R.M.A.; Ariffin Z.Z.; Abidin I.Z.Z.; Senafi S.; Ariffin S.H.Z.
Profiles of inflammatory markers for Traumatised and nontraumatised incisors during orthodontic treatment with two archwire changes
author_facet Yamamoto Z.; Jaafar I.M.; Wahab R.M.A.; Ariffin Z.Z.; Abidin I.Z.Z.; Senafi S.; Ariffin S.H.Z.
author_sort Yamamoto Z.; Jaafar I.M.; Wahab R.M.A.; Ariffin Z.Z.; Abidin I.Z.Z.; Senafi S.; Ariffin S.H.Z.
title Profiles of inflammatory markers for Traumatised and nontraumatised incisors during orthodontic treatment with two archwire changes
title_short Profiles of inflammatory markers for Traumatised and nontraumatised incisors during orthodontic treatment with two archwire changes
title_full Profiles of inflammatory markers for Traumatised and nontraumatised incisors during orthodontic treatment with two archwire changes
title_fullStr Profiles of inflammatory markers for Traumatised and nontraumatised incisors during orthodontic treatment with two archwire changes
title_full_unstemmed Profiles of inflammatory markers for Traumatised and nontraumatised incisors during orthodontic treatment with two archwire changes
title_sort Profiles of inflammatory markers for Traumatised and nontraumatised incisors during orthodontic treatment with two archwire changes
publishDate 2014
container_title Journal of Biological Sciences
container_volume 14
container_issue 4
doi_str_mv 10.3923/jbs.2014.299.304
url https://www.scopus.com/inward/record.uri?eid=2-s2.0-84896449345&doi=10.3923%2fjbs.2014.299.304&partnerID=40&md5=e9503d31448685c0052889eb0fda8a57
description Orthodontic treatment may cause dental root resorption. The risk of dental root resorption increases in orthodontic treated-traumatised teeth. An approach to monitor root resorption is by monitoring inflammatory markers. Therefore, we observed the profiles of inflammatory markers namely Creatine Kinase (CK), nitric oxide (NO), lactate dehydrogenase (LDH) and aspartate aminotransferase (AST) to determine their importance in orthodontic treatment especially in traumatised and nontraumatised incisors. A total of 13 subjects (7 female, 6 male) participated in this study. Samples were collected from gingival crevicular fluid at baseline (M0), 2 weeks after 0.014 NiTi archwire (Ml) and 2 weeks after 0.018 NiTi archwire (M2). All enzyme activities were measured spectrophotometrically at 340 nm. Griess assay was used to measure nitric oxide level. The NO concentration and activities of CK, LDH and AST were not significantly different between traumatised and nontraumatised incisors groups during observation period (p>0.05). Compared to Ml, NO concentration decreased significantly in M2. Other comparisons of all four markers over period of archwire changes in both traumatised and nontraumatised incisors groups showed no significant differences. Inflammatory markers showed different activities or level as responses to previous archwire usage and archwire changes. All markers are not sensitive enough to be categorized as inflammatory markers during orthodontic treatment with two archwire changes. © 2014 Asian Network for Scientific Information.
publisher Asian Network for Scientific Information
issn 17273048
language English
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