Antioxidant properties of phenolic Schiff bases: Structure-activity relationship and mechanism of action

QR Code

Antioxidant properties of phenolic Schiff bases: Structure-activity relationship and mechanism of action

Phenolic Schiff bases are known for their diverse biological activities and ability to scavenge free radicals. To elucidate (1) the structure-antioxidant activity relationship of a series of thirty synthetic derivatives of 2-methoxybezohydrazide phenolic Schiff bases and (2) to determine the major m...

Full description

Bibliographic Details
Published in:	Journal of Computer-Aided Molecular Design
Main Author:	Anouar E.H.; Raweh S.; Bayach I.; Taha M.; Baharudin M.S.; Di Meo F.; Hasan M.H.; Adam A.; Ismail N.H.; Weber J.-F.F.; Trouillas P.
Format:	Article
Language:	English
Published:	Kluwer Academic Publishers 2013
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-84890856883&doi=10.1007%2fs10822-013-9692-0&partnerID=40&md5=8731ef74cbdc13d2a8d02de1b625ed88

Similar Items

Oligostilbenoids from the heartwood of N. Heimii: Role of non-covalent association in their biogenesis
by: Bayach I.; Manshoor N.; Sancho-García J.C.; Choudhary M.I.; Trouillas P.; Weber J.-F.F.
Published: (2015)

Synthesis and antiurease & antioxidant activities of bis-Schiff bases of isophthalaldehyde
by: Rahim F.; Waseeq-Ur-Rehamn; Shehzad M.; Khan A.; Taha M.; Abid O.U.R.; Quereshi M.T.; Tauseef I.; Rehman W.
Published: (2016)

Synthesis of symmetrical bis-Schiff base-disulfide hybrids as highly effective anti-leishmanial agents
by: Taha M.; Sain A.A.; Ali M.; Anouar E.H.; Rahim F.; Ismail N.H.; Adenan M.I.; Imran S.; Al-Harrasi A.; Nawaz F.; Iqbal N.; Khan K.M.
Published: (2020)

Quantification of total phenolic compound and in vitro antioxidant potential of fruit peel extracts
by: Marina Z.; Noriham A.
Published: (2014)

Structure and absolute configuration of 20β-hydroxyprednisolone, a biotransformed product of predinisolone by the marine endophytic fungus penicilium lapidosum
by: Sultan S.; Zaimi Bin Mohd Noor M.; Anouar E.H.; Shah S.A.A.; Salim F.; Rahim R.; Trabolsy Z.B.K.A.; Weber J.-F.F.
Published: (2014)

Synthesis, in vitro biological screening and docking study of benzo[d]oxazole bis Schiff base derivatives as a potent anti-Alzheimer agent
by: Taha M.; Rahim F.; Zaman K.; Anouar E.H.; Uddin N.; Nawaz F.; Sajid M.; Khan K.M.; Shah A.A.; Wadood A.; Rehman A.U.; Alhibshi A.H.
Published: (2023)

X-ray Diffraction, Electronic Circular Dichroism, and Quantum Mechanics (TD-DFT) Investigations on 4-Dehydroxyaltersolanol A, a Secondary Metabolite from Endophytic Fungus Nigrospora oryzae
by: Hussain F.B.M.; Sultan S.; Bayach I.; Naz H.; Singh G.K.S.; Shah S.A.A.; Ashraf K.; Salim F.; Weber J.-F.F.
Published: (2024)

Phenolic content, antioxidant activity and biodiversity changes during spontaneous fermentation of Carica Papaya leaf
by: So’Aib M.S.; Hamid K.H.K.; Salihon J.; Ling T.H.
Published: (2020)

Total phenolic content and antioxidant activity of Pandanus amaryllifolius by soaking and microwave-assisted extraction
by: Asyikin Md Zaki N.; Abd Hashib S.; Kalthum Ibrahim U.; Ani Narisa Ahmad Bakhtiar P.
Published: (2020)

Total phenolic content, total flavonoid content, antioxidant and antimicrobial activities of Malaysian Shorea
by: Ahmat N.; Norizan N.; Mohamad S.A.S.; Nazri N.A.A.M.; Ramli S.S.A.; Kasim S.N.M.; Zain W.Z.W.M.
Published: (2012)

Total phenolic content, flavonoid concentration and antioxidant activity of indigenous herbs, Physalis minima linn
by: Nurhaslina C.R.; Mealianny H.; Mustapa A.N.; Mohd Azizi C.Y.
Published: (2019)

Effect of different cocoa mass levels on total phenolic content, antioxidant activity, and sensory acceptability of panned dark chocolate
by: Ishak I.; Musa N.; Hasim N.A.M.; Hisham N.A.B.; Fadzilah F.N.H.; Khaironi J.; Ahmad F.; Kamarudin W.S.S.W.
Published: (2024)

Impact of drying and extraction method on antioxidant capacity, phenolic compounds and betalain pigment of Alternanthera sessilis red
by: Shaharuddin S.; Othman A.; Ismail A.
Published: (2023)

Tetradentate phenolic Schiff base ligands derived from aromatic diamine and their nickel (II) complexes: Synthesis, characterization, and in vitro anticancer screening
by: Ahmad S.N.; Bahron H.; Tajuddin A.M.; Ramasamy K.
Published: (2019)

Antioxidant Potential of Calophyllum gracilentum: A Study on Total Phenolic Content, Total Flavonoid Content, and Free Radical Scavenging Activities
by: Seruji N.M.U.; Mian V.J.Y.; Zamakshari N.H.; Karunakaran T.; Koo L.F.; Jin W.T.; Huat C.T.
Published: (2023)

Greener approaches to improve phenolic acid composition and antioxidant activity of different cultivation methods of Zingiber officinale Roscoe extracts
by: Nur Diyana A.; Nor Azlan S.N.; Mohd Lazim M.I.; Hussin A.; Mansor A.; Ibrahim A.H.
Published: (2023)

Green Phenolic Resins from Oil Palm Empty Fruit Bunch (EFB) Phenolated Lignin and Bio-Oil as Phenol Substitutes for Bonding Plywood
by: Lim K.Y.; Yasim-Anuar T.A.T.; Sharip N.S.; Ujang F.A.; Husin H.; Ariffin H.; Md Tahir P.; Li X.; Lee S.H.; Yusof M.T.
Published: (2023)

Semipurified Ethyl Acetate Partition of Methanolic Extract of Melastoma malabathricum Leaves Exerts Gastroprotective Activity Partly via Its Antioxidant-Antisecretory-Anti-Inflammatory Action and Synergistic Action of Several Flavonoid-Based Compounds
by: Ismail Suhaimy N.W.; Noor Azmi A.K.; Mohtarrudin N.; Omar M.H.; Tohid S.F.M.; Cheema M.S.; Teh L.K.; Salleh M.Z.; Zakaria Z.A.
Published: (2017)

Antioxidant, anti-inflammatory and antinociceptive activities of Mitragyna speciosa and Erythroxylum cuneatum
by: Saleh S.R.; Hasan M.H.; Said M.I.M.; Adenan M.I.; Adam A.
Published: (2012)

Chemical and pharmacognostical characterization of two Malaysian plants both known as Ajisamat
by: Mohamad T.A.S.T.; Naz H.; Jalal R.S.; Hussin K.; Rahman M.R.A.; Adam A.; Weber J.-F.F.
Published: (2013)

Hepatoprotective action of various partitions of methanol extract of Bauhinia purpurea leaves against paracetamol-induced liver toxicity: Involvement of the antioxidant mechanisms
by: Zakaria Z.A.; Yahya F.; Mamat S.S.; Mahmood N.D.; Mohtarrudin N.; Taher M.; Hamid S.S.A.; Teh L.K.; Salleh M.Z.
Published: (2016)

Synthesis of novel bisindolylmethane Schiff bases and their antibacterial activity
by: Imran S.; Taha M.; Ismail N.H.; Khan K.M.; Naz F.; Hussain M.; Tauseef S.
Published: (2014)

Acylhydrazide schiff bases: Synthesis and antiglycation activity
by: Khan K.M.; Taha M.; Rahim F.; Fakhri M.I.; Jamil W.; Khan M.; Rasheed S.; Karim A.; Perveen S.; Choudhary M.I.
Published: (2013)

Antiglycation and antioxidant potential of novel imidazo[4,5-b]pyridine benzohydrazones
by: Taha M.; Alkadi K.A.A.; Ismail N.H.; Imran S.; Adam A.; Kashif S.M.; Shah S.A.A.; Jamil W.; Sidiqqui S.; Khan K.M.
Published: (2019)

Global Mapping of Traditional Chinese Medicine into Bioactivity Space and Pathways Annotation Improves Mechanistic Understanding and Discovers Relationships between Therapeutic Action (Sub)classes
by: Mohamad Zobir S.Z.; Mohd Fauzi F.; Liggi S.; Drakakis G.; Fu X.; Fan T.-P.; Bender A.
Published: (2016)

Understanding the mode-of-action of Cassia auriculata via in silico and in vivo studies towards validating it as a long term therapy for type II diabetes
by: Mohd Fauzi F.; John C.M.; Karunanidhi A.; Mussa H.Y.; Ramasamy R.; Adam A.; Bender A.
Published: (2017)

X-ray Diffraction, Electronic Circular Dichroism, and Quantum Mechanics (TD-DFT) Investigations on 4-Dehydroxyaltersolanol A, a Secondary Metabolite from Endophytic Fungus Nigrospora oryzae
by: Hussain, et al.
Published: (2024)

Synthesis and in vitro acetylcholinesterase and butyrylcholinesterase inhibitory potential of hydrazide based Schiff bases
by: Rahim F.; Ullah H.; Taha M.; Wadood A.; Javed M.T.; Rehman W.; Nawaz M.; Ashraf M.; Ali M.; Sajid M.; Ali F.; Khan M.N.; Khan K.M.
Published: (2016)

Identification of bisindolylmethane-hydrazone hybrids as novel inhibitors of β-glucuronidase, DFT, and in silico SAR intimations
by: Taha M.; Ismail N.H.; Imran S.; Anouar E.H.; Ali M.; Jamil W.; Uddin N.; Kashif S.M.
Published: (2016)

Synthesis of diindolylmethane (DIM) bearing thiadiazole derivatives as a potent urease inhibitor
by: Taha M.; Rahim F.; Khan A.A.; Anouar E.H.; Ahmed N.; Shah S.A.A.; Ibrahim M.; Zakari Z.A.
Published: (2020)

Synthesis of benzimidazole–based analogs as anti alzheimer’s disease compounds and their molecular docking studies
by: Adalat B.; Rahim F.; Taha M.; Alshamrani F.J.; Anouar E.H.; Uddin N.; Shah S.A.A.; Ali Z.; Zakaria Z.A.
Published: (2020)

Anti-cancer potential of benzophenone-bis-Schiff bases on human pancreatic cancer cell line
by: Khan K.M.; Rasheed H.; Fatima B.; Hayat M.; Rahim F.; Ullah H.; Hameed A.; Taha M.; Tahir A.; Perveen S.
Published: (2016)

Assessment of antioxidant activity and total phenolic content from green coffee Robusta sp. beans; [Penilaian aktiviti antioksidan dan kandungan jumlah fenolik dari biji kopi Robusta sp. hijau]
by: Siva R.; Rajikin N.; Haiyee Z.A.; Ismail W.I.W.
Published: (2016)

3,4-Dimethoxybenzohydrazide derivatives as antiulcer: Molecular modeling and density functional studies
by: Taha M.; Ismail N.H.; Zaki H.M.; Wadood A.; Anouar E.H.; Imran S.; Yamin B.M.; Rahim F.; Ali M.; Khan K.M.
Published: (2017)

Apoptosis induction by polygonum minus is related to antioxidant capacity, alterations in expression of apoptotic-related genes, and S-phase cell cycle arrest in HepG2 cell line
by: Mohd Ghazali M.A.; Al-Naqeb G.; Krishnan Selvarajan K.; Hazizul Hasan M.; Adam A.
Published: (2014)

Evaluation of cytotoxic and tyrosinase inhibitory activities of 2-phenoxy(Thiomethyl) pyridotriazolopyrimidines: In vitro and molecular docking studies
by: Abuelizz H.A.; Anouar E.H.; Marzouk M.; Hasan M.H.; Saleh S.R.; Ahudhaif A.; Alburikan K.A.; Al-Salahi R.
Published: (2020)

Isatin based Schiff bases as inhibitors of α-glucosidase: Synthesis, characterization, in vitro evaluation and molecular docking studies
by: Rahim F.; Malik F.; Ullah H.; Wadood A.; Khan F.; Javid M.T.; Taha M.; Rehman W.; Ur Rehman A.; Khan K.M.
Published: (2015)

Piano Teaching Action Recognition Based on LSTM
by: Sha R.; Tan B.
Published: (2024)

Optical absorbance of RGB LEDs in pH measurement of colorimetric solution with phenol red reagent
by: Maidan Dali M.R.; Azam A.S.; Abd Rahman M.F.; Ahmad K.A.; Othman N.A.; Abdullah M.H.; Omar A.F.
Published: (2022)

Synthesis and biological evaluation of substituted benzohydrazide Schiff base adduct as potential cholinesterase inhibitors
by: Zulfiqar A.; Khan I.U.; Nabi M.; Ullah H.; Iqbal N.; Zeb B.; Hussain A.; Khan D.; Rab A.; Junaid S.M.; Taha M.; Shah S.A.A.; Rahim F.
Published: (2024)