DNA methylation profiling revealed promoter hypermethylation-induced silencing of p16, DDAH2 and DUSP1 in primary oral squamous cell carcinoma

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DNA methylation profiling revealed promoter hypermethylation-induced silencing of p16, DDAH2 and DUSP1 in primary oral squamous cell carcinoma

Background: Hypermethylation in promoter regions of genes might lead to altered gene functions and result in malignant cellular transformation. Thus, biomarker identification for hypermethylated genes would be very useful for early diagnosis, prognosis, and therapeutic treatment of oral squamous cel...

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Bibliographic Details
Published in:	International Journal of Medical Sciences
Main Author:	Khor G.H.; Froemming G.R.A.; Zain R.B.; Thomas Abraham M.; Omar E.; Tan S.K.; Tan A.C.; Vincent-Chong V.K.; Thong K.L.
Format:	Article
Language:	English
Published:	2013
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-84885896729&doi=10.7150%2fijms.6884&partnerID=40&md5=4f6361095ea471369cba4590d8d2b28b

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