| Summary: | Zingiber officinale Roscoe, family of Zingiberaceae is classified as traditional medicinalthat globally consumed as spices, food flavouring as well as remedies to treat women duringconfinement, to treat stomach upset and diarrhoea.The rhizome has been reported to containabundant bioactive constituents which are mainly polyphenol and flavonoid. Therefore in thisresearch the effect of cabinet drying (60°C) and freeze drying (-40°C) process during preparation ofnanostructure Zingiber officinale Roscoe rhizome on particle sizes, surface morphology, FTIR, aswell as Total Phenolic Content (TPC) and Total Flavonoid Content(TFC) were compared. Bothdrying process affect the particle sizes as well as TPC and TFC value. Finer particle size (254.3±9.33) and higher TPC (152.54 mg GAE/ g) and TFC (1.42 mgQE/g) were reported for cabinet driednanostructure Zingiber officinale Rosc. rhizome as compared to freeze dried. The FESEMPhotographs revealed that drying processes did affect the surface morphologies of nanostructureZingiber officinale Rosc rhizome where cabinet dried produced solid spherical particles with adiameter around 100 - 200 nm and some smaller than100nm. Freeze dried consist of manynanoparticles having rod like structure. Both drying process did not significantly affect the presenceof active compounds based on FTIR analysis. © (2013) Trans Tech Publications, Switzerland.
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