The potential role of inflammatory cytokines as useful diagnostic indicators in osseointegrated dental implants

The aim of this study was to measure the levels of selected cytokines; interleukin-1 (IL-1), interleukin- 8 (IL-8) and granulocyte-macrophage colony stimulating factor (GM-CSF) to evaluate their implication in periimplant inflammation and their influence upon osseointegration, with a view to establi...

Full description

Bibliographic Details
Published in:World Applied Sciences Journal
Main Author: Al Duboni G.; Osman M.T.; Taha B.I.; Muhamed L.A.
Format: Article
Language:English
Published: International Digital Organization for Scientific Information 2012
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84871872908&partnerID=40&md5=9ba197d7d50094e74f383fea6aab7744
id 2-s2.0-84871872908
spelling 2-s2.0-84871872908
Al Duboni G.; Osman M.T.; Taha B.I.; Muhamed L.A.
The potential role of inflammatory cytokines as useful diagnostic indicators in osseointegrated dental implants
2012
World Applied Sciences Journal
20
5

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84871872908&partnerID=40&md5=9ba197d7d50094e74f383fea6aab7744
The aim of this study was to measure the levels of selected cytokines; interleukin-1 (IL-1), interleukin- 8 (IL-8) and granulocyte-macrophage colony stimulating factor (GM-CSF) to evaluate their implication in periimplant inflammation and their influence upon osseointegration, with a view to establish whether increased cytokine concentrations in the serum and or periimplant sulcus. 156 subjects (106 partially edentulous patients and 50 healthy controls); mean age, 25 years) were attending the Department of Maxillofacial Surgery in Specialized Surgeries Hospital, Medical City, Baghdad, Iraq. Subjects were grouped in to group1 consisted of 85 patients with working osseointegrated implants, group 2 consisted of 21 patients with at least one failed or diseased implants and group 3 was consisted of 50 randomly taken healthy control adult subjects (25 subjects of each sex). Enzyme-linked immunosorbent assay (ELISA) kits were used for analysis and detection of IL-1 •, IL-8 and GM-CSF in the patient sera and their periimplant sulcular fluid (PISF) specimens.The elevated PISF and serum levels of selected inflammatory cytokines is a result of their activation in the inflammatory process of the periimplantitis, however this activation may contribute to periimplant supportive tissue destruction and bone loss. © IDOSI Publications, 2012.
International Digital Organization for Scientific Information
18184952
English
Article

author Al Duboni G.; Osman M.T.; Taha B.I.; Muhamed L.A.
spellingShingle Al Duboni G.; Osman M.T.; Taha B.I.; Muhamed L.A.
The potential role of inflammatory cytokines as useful diagnostic indicators in osseointegrated dental implants
author_facet Al Duboni G.; Osman M.T.; Taha B.I.; Muhamed L.A.
author_sort Al Duboni G.; Osman M.T.; Taha B.I.; Muhamed L.A.
title The potential role of inflammatory cytokines as useful diagnostic indicators in osseointegrated dental implants
title_short The potential role of inflammatory cytokines as useful diagnostic indicators in osseointegrated dental implants
title_full The potential role of inflammatory cytokines as useful diagnostic indicators in osseointegrated dental implants
title_fullStr The potential role of inflammatory cytokines as useful diagnostic indicators in osseointegrated dental implants
title_full_unstemmed The potential role of inflammatory cytokines as useful diagnostic indicators in osseointegrated dental implants
title_sort The potential role of inflammatory cytokines as useful diagnostic indicators in osseointegrated dental implants
publishDate 2012
container_title World Applied Sciences Journal
container_volume 20
container_issue 5
doi_str_mv
url https://www.scopus.com/inward/record.uri?eid=2-s2.0-84871872908&partnerID=40&md5=9ba197d7d50094e74f383fea6aab7744
description The aim of this study was to measure the levels of selected cytokines; interleukin-1 (IL-1), interleukin- 8 (IL-8) and granulocyte-macrophage colony stimulating factor (GM-CSF) to evaluate their implication in periimplant inflammation and their influence upon osseointegration, with a view to establish whether increased cytokine concentrations in the serum and or periimplant sulcus. 156 subjects (106 partially edentulous patients and 50 healthy controls); mean age, 25 years) were attending the Department of Maxillofacial Surgery in Specialized Surgeries Hospital, Medical City, Baghdad, Iraq. Subjects were grouped in to group1 consisted of 85 patients with working osseointegrated implants, group 2 consisted of 21 patients with at least one failed or diseased implants and group 3 was consisted of 50 randomly taken healthy control adult subjects (25 subjects of each sex). Enzyme-linked immunosorbent assay (ELISA) kits were used for analysis and detection of IL-1 •, IL-8 and GM-CSF in the patient sera and their periimplant sulcular fluid (PISF) specimens.The elevated PISF and serum levels of selected inflammatory cytokines is a result of their activation in the inflammatory process of the periimplantitis, however this activation may contribute to periimplant supportive tissue destruction and bone loss. © IDOSI Publications, 2012.
publisher International Digital Organization for Scientific Information
issn 18184952
language English
format Article
accesstype
record_format scopus
collection Scopus
_version_ 1812871802226999296