Clinical relevance of VKORC1 (G-1639A and C1173T) and CYP2C9*3 among patients on warfarin

QR Code

Clinical relevance of VKORC1 (G-1639A and C1173T) and CYP2C9*3 among patients on warfarin

What is known and Objectives: Testing for cytochrome P450-2C9 (CYP2C9) and vitamin K epoxide reductase complex subunit 1 (VKORC1) variant alleles is recommended by the FDA for dosing of warfarin. However, dose prediction models derived from data obtained in one population may not be applicable to an...

Full description

Bibliographic Details
Published in:	Journal of Clinical Pharmacy and Therapeutics
Main Author:	Teh L.K.; Langmia I.M.; Fazleen Haslinda M.H.; Ngow H.A.; Roziah M.J.; Harun R.; Zakaria Z.A.; Salleh M.Z.
Format:	Article
Language:	English
Published:	2012
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-84857946108&doi=10.1111%2fj.1365-2710.2011.01262.x&partnerID=40&md5=c11f16571a9381ef4498e3894b730ba8

Similar Items

Malaysian Indians are genetically similar to Caucasians: CYP2C9 polymorphism
by: Zainuddin Z.; Teh L.K.; Suhaimi A.W.M.; Ismail R.
Published: (2006)

Genetic polymorphism of CYP2C8 in three Malaysian ethnics: CYP2C8*2 and CYP2C8*3 are found in Malaysian Indians
by: Muthiah Y.D.; Lee W.L.; Teh L.K.; Ong C.E.; Ismail R.
Published: (2005)

Systematic characterization and comparison of the CYP2C9 variability of the Orang Asli in Malaysia with 12 populations
by: Teh L.K.; Subramaniam V.; Tuan Abdu Aziz T.A.; Lee L.S.; Ismail M.I.; Yu C.Y.; Ang G.Y.; James Johari R.; Ismet R.I.; Sahak N.S.; Ahmad A.; Rahman T.A.; Nor @ Ghazali F.M.; Shaari S.; Omar M.; Ismail A.I.; Md. Isa K.; Salleh H.; Salleh M.Z.
Published: (2016)

The relevance of CYP2D6 genetic polymorphism on chronic metoprolol therapy in cardiovascular patients
by: Ismail R.; Teh L.K.
Published: (2006)

Mutational analysis of CYP2C8 in hypertensive patients using denaturing high performance liquid chromatography
by: Teh L.K.; Zahri M.K.; Zakaria Z.A.; Ismail R.; Salleh M.Z.
Published: (2010)

C programming: Relevant exercises for engineering students using bloom’s taxonomy
by: Abdul Rahman T.F.B.
Published: (2017)

The implication of the polymorphisms of COX-1, UGT1A6, and CYP2C9 among cardiovascular disease patients treated with aspirin
by: Abdul Jalil N.J.; Bannur Z.; Derahman A.; Maskon O.; Darinah N.; Hamidi H.; Ali O.; Gunasekaran; Rafizi M.; Azreen N.I.; Kek T.L.; Salleh M.Z.
Published: (2015)

Detection of CYP2C19 genetic variants in Malaysian Orang Asli from massively parallel sequencing data
by: Ang G.Y.; Yu C.Y.; Subramaniam V.; Khalid M.I.H.A.; Aziz T.A.T.A.; James R.J.; Ahmad A.; Rahman T.A.; Nor F.M.; Ismail A.I.; Isa K.M.; Salleh H.; Teh L.K.; Salleh M.Z.
Published: (2016)

Effect of standardized warfarin treatment protocol on anticoagulant effect: Comparison of a warfarin medication therapy adherence clinic with usual medical care
by: Aidit S.; Soh Y.C.; Yap C.S.; Khan T.M.; Neoh C.F.; Shaharuddin S.; Kassab Y.W.; Patel R.P.; Ming L.C.
Published: (2017)

The risk of recurrence in breast cancer patients treated with tamoxifen: Polymorphisms of CYP2D6 and ABCB1
by: Teh L.K.; Mohamed N.I.; Salleh M.Z.; Rohaizak M.; Shahrun N.S.; Saladina J.J.; Shia J.K.S.; Roslan H.; Sood S.; Rajoo T.S.; Muniandy S.P.; Henry G.; Ngow H.A.; Hla U K.T.; Din J.
Published: (2012)

Performance Analysis of Heterogeneous Data Transmission in 5G C-V2N Communication
by: Bin Mustaffa M.A.; Binti Zainol Abidin H.; Mazalan L.B.; Hafizhelmi Kamaru Zaman F.; Mun N.K.; Afzal Bin Che Abdullah S.
Published: (2022)

Revealing the impact of different precursors and solvents for supramolecular complex formation and in-situ C-doping in g-C3N4 with enhanced photocatalytic H2O2 production
by: Nordin N.A.; Mohamed M.A.; Mastuli M.S.; Mohd Yusoff S.F.; Sugiura T.; Manseki K.
Published: (2024)

Crystal structure of 5,6,3′,4′,5′-pentamethoxy-flavone dihydrate, C20H24O9
by: Salihu A.S.; Salleh W.M.N.H.W.; Tajuddin A.M.; Ghani N.A.
Published: (2024)

Synergistic interaction and chemically bonded association between ZIF-8 and C-doped g-C3N4 for enhancement of visible light photocatalytic H2O2 production
by: Nordin, et al.
Published: (2024)

Synergistic interaction and chemically bonded association between ZIF-8 and C-doped g-C3N4 for enhancement of visible light photocatalytic H2O2 production
by: Nordin N.A.; Mohamed M.A.; Hasnan N.S.N.; Yusoff S.F.M.; Mastuli M.S.; Sugiura T.; Manseki K.
Published: (2024)

The Construction of CRISPR-Cas9 System Targeting Vector for CYP3A4 Gene in Hepatic Cell Lines
by: Hatta F.H.M.; Aziz F.N.A.; Rehman S.-U.; Othman A.A.
Published: (2025)

Functional Concepts in C++
by: Abdul Rauf R.H.; Berger U.; Setzer A.
Published: (2005)

A Review on the Potential of Application of CRISPR/Cas9 Technology in CYP3A4 and CYP2D6 Genes: A Way to Move Forward in Identifying New Drug Targets
by: Othman A.; Yusoff R.M.; Azam S.N.N.; Hassan A.Z.A.; Hatta F.H.
Published: (2022)

PHOTOCATALYTIC DEGRADATION OF OFLOXACIN ANTIBIOTIC BY g-C3N4/ZnO NANOCOMPOSITE UNDER VISIBLE LIGHT IRRADIATION; [Fotokatalitik Degradasi Ofloksasin Antibiotik oleh Nanokomposit g-C3N4/ZnO di Bawah Penyinaran Cahaya Tampak]
by: Chayed N.F.; Mashuri S.I.S.; Abidin I.S.Z.; Kasim M.F.; Kaus N.H.M.; Mastuli M.S.; Rashid U.; Ibrahim M.L.
Published: (2023)

Recent Advancement of the Current Aspects of g-C3N4 for its Photocatalytic Applications in Sustainable Energy System
by: Hayat A.; Sohail M.; Ali Shah Syed J.; Al-Sehemi A.G.; Mohammed M.H.; Al-Ghamdi A.A.; Taha T.A.; Salem AlSalem H.; Alenad A.M.; Amin M.A.; Palamanit A.; Liu C.; Nawawi W.I.; Tariq Saeed Chani M.; Muzibur Rahman M.
Published: (2022)

Nanostructured materials based on g-C3N4 for enhanced photocatalytic activity and potentials application: A review
by: Sohail M.; Anwar U.; Taha T.A.; Qazi H.I.A.; Al-Sehemi A.G.; Ullah S.; Algarni H.; Ahmed I.M.; Amin M.A.; Palamanit A.; Iqbal W.; Alharthi S.; Nawawi W.I.; Ajmal Z.; Ali H.; Hayat A.
Published: (2022)

Multichannel Microstimulating SoC
by: Noorsal E.; Xu H.; Sooksood K.; Ortmanns M.
Published: (2022)

Polymorphism of ITPA 94C>A and risk of adverse effects among patients with acute lymphoblastic leukaemia treated with 6-mercaptopurine
by: Wan Rosalina W.R.; Teh L.K.; Mohamad N.; Nasir A.; Yusoff R.; Baba A.A.; Salleh M.Z.
Published: (2012)

PHYSICOCHEMICAL CHARACTERIZATION OF ZnO/G-C3 N4 FOR PHOTO-REMOVAL OF METHYL ORANGE UNDER LOW UV-LIGHT INTENSITY; [Pencirian Fizikokimia ZnO/g-C3N4 untuk Penyingkiran Metil Oren di Bawah Lampu UV Berkeamatan Rendah]
by: Izhar N.I.; Hir Z.A.M.; Rafaie H.A.; Daud S.
Published: (2024)

Palladium Complexes Derived from Waste as Catalysts for C-H Functionalisation and C-N Bond Formation
by: Jantan K.A.; Ekart G.; McCarthy S.; White A.J.P.; Braddock D.C.; Serpe A.; Wilton-Ely J.D.E.T.
Published: (2024)

Chemical changes in shortfin SCAD (Decapterus macrosoma) at chilled (4°C) and frozen (-18°C) storage; [Perubahan kimia dalam ikan selayang (Decapterus macrosoma) pada penyimpanan suhu dingin (4°C) dan sejuk beku (-18°C)]
by: Juhari F.F.; Abd. Rashid N.; Seng C.C.; Yusoff A.; Mohd Bakri E.A.
Published: (2016)

Taxonomy of C overflow vulnerabilities attack
by: Ahmad N.H.; Aljunid S.A.; Ab Manan J.-L.
Published: (2011)

A facile molecular aggregation of isoquinoline based g-C3N4 for high photocatalytic performance under visible light illumination
by: Pan F.; Sohail M.; Taha T.A.; Al-Sehemi A.G.; Ullah S.; AlSalem H.S.; Mersal G.A.; Ibrahim M.M.; Alenad A.M.; Al-Hartomy O.A.; Amin M.A.; Ajmal Z.; Palamanit A.; Hayat A.; Zada A.; Nawawi W.I.
Published: (2022)

Pharmacogenotyping of CYP3A5 in predicting dose-adjusted trough levels of tacrolimus among Malaysian kidney-transplant patients
by: Hamzah S.; Teh L.K.; Siew J.S.K.; Ahmad G.; Wong H.S.; Zakaria Z.A.; Salleh M.Z.
Published: (2014)

A Targeted Review of Current Progress, Challenges and Future Perspective of g-C3N4 based Hybrid Photocatalyst Toward Multidimensional Applications
by: Hayat A.; Sohail M.; Anwar U.; Taha T.A.; Qazi H.I.A.; Amina; Ajmal Z.; Al-Sehemi A.G.; Algarni H.; Al-Ghamdi A.A.; Amin M.A.; Palamanit A.; Nawawi W.I.; Newair E.F.; Orooji Y.
Published: (2023)

In vivo study of homoeopathic preparation of Gymnema sylvestre mother tincture, 30C and 200C on streptozotocin-induced diabetic rats
by: Shukla A.; Mhaisker I.U.; Rampal K.G.; Sheshala R.
Published: (2021)

Facile synthesis and characterization of a visible light-active ternary TiO2/ZnS/g-C3N4 heterostructure for multipollutant degradation
by: Kanakaraju D.; Chandrasekaran A.; Lim Y.C.
Published: (2024)

Aqua-Mediated Hydrothermal Synthesis in the Production of a g- C3N4/TiO2Composite for Photocatalytic Degradation of RR4 Dye
by: Muhamad N.A.; Rosli M.A.; Hamzah S.R.; Ghani N.I.A.; Md Natar N.S.; Mohd Azami M.S.; Mohd Ishak M.A.; Sabar S.; Ismail W.I.N.W.
Published: (2024)

Facile synthesis and characterization of a visible light-active ternary TiO2/ZnS/g-C3N4 heterostructure for multipollutant degradation
by: Kanakaraju, et al.
Published: (2024)

Palladium and copper catalyzed Sonogashira cross coupling has been an excellent methodology for C-C bond formation for 17 years: A review
by: Kanwal I.; Mujahid A.; Rasool N.; Rizwan K.; Malik A.; Ahmad G.; Shah S.A.A.; Rashid U.; Nasir N.M.
Published: (2020)

The New Material Battery Based on Mg/C-π
by: Siburian R.; Paiman S.; Hutagalung F.; Ali A.M.M.; Simatupang L.; Simanjuntak C.
Published: (2021)

Inference of the Genetic Polymorphisms of CYP2D6 in Six Subtribes of the Malaysian Orang Asli from Whole-Genome Sequencing Data
by: Yu C.Y.; Ang G.Y.; Subramaniam V.; Johari James R.; Ahmad A.; Abdul Rahman T.; Mohd Nor F.; Shaari S.A.; Teh L.K.; Salleh M.Z.
Published: (2017)

Knots timber detection and classification with C-support vector machine
by: Redzuan F.I.M.; Yusoff M.
Published: (2019)

Pressure-induced enhancement of mechanical performance in ZrC system
by: Yong Y.S.; Chang Y.H.R.; Low L.C.; Lim T.L.; Yoon T.L.
Published: (2022)

Volatile–char interactions during biomass pyrolysis: Cleavage of C–C bond in a β–5 lignin model dimer by amino-modified graphitized carbon nanotube
by: Huang Y.; Liu S.; Zhang J.; Syed-Hassan S.S.A.; Hu X.; Sun H.; Zhu X.; Zhou J.; Zhang S.; Zhang H.
Published: (2020)