Polyamidoamine dendrimers can improve the pulmonary absorption of insulin and calcitonin in rats

The absorption-enhancing effects of polyamidoamine (PAMAM) dendrimers with various generations (G0-G3) and concentrations [0.1%-1.0% (w/v)] on the pulmonary absorption of peptide and protein drugs were studied in rats. Insulin and calcitonin were chosen as models of peptide and protein drugs, and th...

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Bibliographic Details
Published in:Journal of Pharmaceutical Sciences
Main Author: Dong Z.; Hamid K.A.; Gao Y.; Lin Y.; Katsumi H.; Sakane T.; Yamamoto A.
Format: Article
Language:English
Published: John Wiley and Sons Inc. 2011
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-79952224936&doi=10.1002%2fjps.22428&partnerID=40&md5=0bc27cdbe0d7ce957e7e5d8bfc6b22fd