Mutational analysis of CYP2C8 in hypertensive patients using denaturing high performance liquid chromatography

What is known and Objective: CYP2C8 is involved in the cytochrome P450 (CYP) epoxygenase pathway. Arachidonic acid metabolites such as epoxyeicosatrienenoic acids and hydroxyeicosatetrenoic acids, produced may have a role in hypertension. We aimed to develop a medium through-put method for screening...

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Bibliographic Details
Published in:Journal of Clinical Pharmacy and Therapeutics
Main Author: Teh L.K.; Zahri M.K.; Zakaria Z.A.; Ismail R.; Salleh M.Z.
Format: Article
Language:English
Published: 2010
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-78449286775&doi=10.1111%2fj.1365-2710.2009.01146.x&partnerID=40&md5=5b3595bf10c0c77f5251cd9ad29929bc