Antiproliferative properties of clausine-B against cancer cell lines

QR Code

Antiproliferative properties of clausine-B against cancer cell lines

Background: Clausine B, a carbazole alkaloid isolated from the stem bark of Clausena excavata, was investigated for its antiproliferative activities against five human cancer cell lines: HepG2 (hepatic cancer), MCF-7 (hormone-dependent breast cancer), MDA-MB-231 (non-hormone-dependent breast cancer)...

Full description

Bibliographic Details
Published in:	Malaysian Journal of Medical Sciences
Main Author:	Wan Mohd Zain W.N.I.; Rahmat A.; Othman F.; Yap T.Y.H.
Format:	Article
Language:	English
Published:	2009
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-73449143149&partnerID=40&md5=4b2bf19a0dadf082e662621ac83c4539

Similar Items

Gelam (Melaleuca sp.) honey demonstrates antiproliferative effect on colon cancer cell lines (HCT116)
by: Fadhli M.R.M.N.; Noorfathiah I.; Hana M.A.N.F.; Ashraf M.S.M.; Zolkapli E.; Mizaton H.H.; Iryani W.I.W.
Published: (2012)

Investigation of antiproliferative mechanisms of Alstonia angustiloba-silver nanoparticles in skin squamous cell carcinoma (A431 cell line)
by: Rahim N.A.; Mail M.H.; Muhamad M.; Sapuan S.; SMN Mydin R.B.; Seeni A.
Published: (2022)

Cytotoxicity and Genotoxicity of Biogenic Silver Nanoparticles in A549 and BEAS-2B Cell Lines
by: Muhamad M.; Ab.rahim N.; Wan Omar W.A.; Nik Mohamed Kamal N.N.S.
Published: (2022)

Anti-cancer potential of benzophenone-bis-Schiff bases on human pancreatic cancer cell line
by: Khan K.M.; Rasheed H.; Fatima B.; Hayat M.; Rahim F.; Ullah H.; Hameed A.; Taha M.; Tahir A.; Perveen S.
Published: (2016)

Synthesis of damnacanthal, a naturally occurring 9,10-anthraquinone and its analogues, and its biological evaluation against five cancer cell lines
by: Saha K.; Lam K.W.; Abas F.; Sazali Hamzah A.; Stanslas J.; Hui L.S.; Lajis N.H.
Published: (2013)

The Association of Sugar and Sugar Substitutes to Breast, Lung, and Oral Cancer Cell Lines: A Scoping Review
by: Zainal, et al.
Published: (2023)

Cytotoxicity of anchusa arvensis against HepG-2 cell lines: Mechanistic and computational approaches
by: Hussain S.; Ullah F.; Sadiq A.; Ayaz M.; Shah A.-U.-H.A.; Shah S.A.A.; Shah S.M.; Nadhman A.; Ullah F.; Wadood A.; El-Shazly M.
Published: (2019)

The Association of Sugar and Sugar Substitutes to Breast, Lung, and Oral Cancer Cell Lines: A Scoping Review
by: Zainal M.; Md Asri N.S.; Mohamed Faizal N.S.; Khan H.B.S.G.; Kamil W.N.W.A.; Mohd Sarmin N.I.; Mohd Kornain N.K.; Arzmi M.H.
Published: (2023)

Chemical Constituents and Antiproliferative Activity of Eleusine indica (L.) Gaertn
by: Sukor S.; Zahari Z.; Rahim N.; Yusoff J.; Salim F.
Published: (2022)

Bio-Oriented Synthesis and Molecular Docking Studies of 1,2,4-Triazole Based Derivatives as Potential Anti-Cancer Agents against HepG2 Cell Line
by: Akhter N.; Batool S.; Khan S.G.; Rasool N.; Anjum F.; Rasul A.; Adem Ş.; Mahmood S.; Rehman A.U.; Nisa M.U.; Razzaq Z.; Christensen J.B.; Abourehab M.A.S.; Shah S.A.A.; Imran S.
Published: (2023)

Synthesis and biological evaluation of chromone derivatives against triple-negative breast cancer cells
by: Islam R.; Yan M.P.; Yen K.P.; Rasol N.E.; Meng C.K.; Wai L.K.
Published: (2023)

P53 and cyclin B1 mediate apoptotic effects of apigenin and rutin in ERα+-breast cancer MCF-7 cells
by: Abdul Hamid Hasani N.; Mohd Amin I.; Kamaludin R.; Nik Mohd Rosdy N.M.M.; Johari Ibahim M.; Sheikh Abdul Kadir S.H.
Published: (2018)

Molecular docking, synthesis and biological significance of pyrimidine analogues as prospective antimicrobial and antiproliferative agents
by: Kumar S.; Kaushik A.; Narasimhan B.; Shah S.A.A.; Lim S.M.; Ramasamy K.; Mani V.
Published: (2019)

Design, synthesis and biological profile of heterocyclic benzimidazole analogues as prospective antimicrobial and antiproliferative agents
by: Tahlan S.; Kumar S.; Ramasamy K.; Lim S.M.; Shah S.A.A.; Mani V.; Pathania R.; Narasimhan B.
Published: (2019)

Combinatorial cytotoxic effects of damnacanthal and doxorubicin against human breast cancer MCF-7 cells in vitro
by: Aziz M.Y.A.; Abu N.; Yeap S.K.; Ho W.Y.; Omar A.R.; Ismail N.H.; Ahmad S.; Pirozyan M.R.; Akhtar N.M.; Alitheen N.B.
Published: (2016)

Graphene oxide/chitosan/manganese/folic acid-brucine functionalized nanocomposites show anticancer activity against liver cancer cells
by: Alzahrani, et al.
Published: (2024)

Goniothalamus umbrosus Induces Cell Cycle Arrest in Oral Squamous Cell Carcinoma Cell Line
by: Aziz N.C.; Alahmad B.E.M.; Kashmoola M.A.; Lestari W.; Mokhtar K.I.; Rosdy N.M.M.N.M.
Published: (2024)

Inhibition of angiogenesis and metastasis in colorectal cancer cell lines through KRAS-associated signaling pathways by 2-methoxy-6-undecyl-1,4-benzoquinone
by: Abd Rahman N.I.; Tham C.L.; Abd Hamid R.
Published: (2024)

Graphene oxide/chitosan/manganese/folic acid-brucine functionalized nanocomposites show anticancer activity against liver cancer cells
by: Alzahrani A.R.; Ibrahim I.A.A.; Alanazi I.M.; Shahzad N.; Shahid I.; Azlina M.F.N.; Kamisah Y.; Ismail N.M.; Arulselvan P.
Published: (2024)

The Roles of Immune Cells in Gastric Cancer: Anti-Cancer or Pro-Cancer?
by: Sukri A.; Hanafiah A.; Kosai N.R.
Published: (2022)

Discovery of Dual Inhibitors of Acetyl and Butrylcholinesterase and Antiproliferative Activity of 1,2,4-Triazole-3-thiol: Synthesis and In Silico Molecular Study
by: Siddiqui S.Z.; Arfan M.; Abbasi M.A.; Aziz-ur-Rehman; Shah S.A.A.; Ashraf M.; Hussain S.; Saleem R.S.Z.; Rafique R.; Khan K.M.
Published: (2020)

Production Rate Improvement for Assembly Line in Sheet Metal Stamping Industry
by: Othman N.L.A.; Zain N.A.M.; Ibrahim D.; Yaacob Y.
Published: (2019)

The Construction of CRISPR-Cas9 System Targeting Vector for CYP3A4 Gene in Hepatic Cell Lines
by: Hatta F.H.M.; Aziz F.N.A.; Rehman S.-U.; Othman A.A.
Published: (2025)

Determination toxic effects of Hystrix Brachyura Bezoar extracts using cancer cell lines and embryo zebrafish (Danio rerio) models and identification of active principles through GC-MS analysis
by: Firus Khan A.Y.; Ahmed Q.U.; Nippun T.S.; Hilles A.; Jalal T.K.; Teh L.K.; Salleh M.Z.; Noor S.M.; Seeni A.; Khatib A.; Wahab R.A.
Published: (2020)

Antibiofilm properties of chemically synthesized silver nanoparticles found against Pseudomonas aeruginosa
by: Palanisamy N.K.; Ferina N.; Amirulhusni A.N.; Mohd-Zain Z.; Hussaini J.; Ping L.J.; Durairaj R.
Published: (2014)

The application of VR panoramic technology in B&B design strategies-taking the B&B in southern anhui as an example
by: Junhua X.; Abidin S.Z.; Vermol V.V.
Published: (2024)

Synthesis, molecular modelling and biological significance of N-(4-(4-bromophenyl) thiazol-2-yl)-2-chloroacetamide derivatives as prospective antimicrobial and antiproliferative agents
by: Sharma D.; Kumar S.; Narasimhan B.; Ramasamy K.; Lim S.M.; Shah S.A.A.; Mani V.
Published: (2019)

New Line Voltage Stability Index (BVSI) for Voltage Stability Assessment in Power System: The Comparative Studies
by: Ismail B.; Wahab N.I.A.; Othman M.L.; Radzi M.A.M.; Vijayakumar K.N.; Rahmat M.K.; Naain M.N.M.
Published: (2022)

Microstructure and mechanical properties investigation of in situ TiB2 and ZrB2 reinforced Al-4Cu composites
by: Anis A.L.; Ramli R.; Darham W.; Zakaria A.; Talari M.K.
Published: (2016)

Protection of Fargesin against Hydrogen Peroxide-induced Cell Death in RAW 264.7 Cells
by: Roof, et al.
Published: (2024)

Tumor Suppressive Effects of GAS5 in Cancer Cells
by: Kaur J.; Salehen N.; Norazit A.; Rahman A.A.; Murad N.A.A.; Rahman N.M.A.N.A.; Ibrahim K.
Published: (2022)

A review of the effects of Calophyllum spp. on cancer cells
by: Kilus M.; Samad N.A.; Daud S.
Published: (2023)

Apoptosis induction by polygonum minus is related to antioxidant capacity, alterations in expression of apoptotic-related genes, and S-phase cell cycle arrest in HepG2 cell line
by: Mohd Ghazali M.A.; Al-Naqeb G.; Krishnan Selvarajan K.; Hazizul Hasan M.; Adam A.
Published: (2014)

PAK5 mediates cell: Cell adhesion integrity via interaction with E-cadherin in bladder cancer cells
by: Ismail A.F.; Halacli S.O.; Babteen N.; De Piano M.; Martin T.A.; Jiang W.G.; Khan M.S.; Dasgupta P.; Wells C.M.
Published: (2017)

Genoprotective potential of Macaranga species phytochemical compounds on HT-29 human colorectal adenocarcinoma cell line
by: Siew E.L.; Pearanpan L.; Zamkhuri Z.; Nordin F.J.; Ooi T.C.; Chan K.M.; Kamarozaman A.S.; Ahmat N.; Rajab N.F.
Published: (2023)

Low concentration of bisphenol a induces proliferation of gastric cancer cells, HGC-27
by: Hanafi N.I.; Kadir S.H.S.A.; Musa M.; Othman M.H.D.; Kamaludin R.; Zulkifli N.A.; Latip N.A.; Karim Z.R.A.
Published: (2019)

Proteomic analysis of anti-cancer effects of Streblus asper root extract on HeLa cancer cells
by: Nabil M.; Seeni A.; Ismail W.I.; Rahim N.A.
Published: (2019)

Prenatal Bisphenol a Exposure and Postnatal Trans Fat Diet Alter Small Intestinal Morphology and Its Global DNA Methylation in Male Sprague-Dawley Rats, Leading to Obesity Development
by: Zulkifli S.; Mohd Nor N.S.; Sheikh Abdul Kadir S.H.; Mohd Ranai N.; Mohd Kornain N.K.; Wan Mohd Zain W.N.I.; Abdul Aziz M.
Published: (2022)

2-mercaptobenzimidazole schiff bases: Design, synthesis, antimicrobial studies and anticancer activity on HCT-116 cell line
by: Tahlan S.; Narasimhan B.; Lim S.M.; Ramasamy K.; Mani V.; Shah S.A.A.
Published: (2019)

YOLO and residual network for colorectal cancer cell detection and counting
by: Haq, et al.
Published: (2024)