6-Benzyl-3-(1,4-dioxaspiro-[4.5]decan-2-yl)-8,8-dimethyl-1-oxa-2, 6-diaza-spiro-[4.4]non-2-ene-7,9-dione

QR Code

6-Benzyl-3-(1,4-dioxaspiro-[4.5]decan-2-yl)-8,8-dimethyl-1-oxa-2, 6-diaza-spiro-[4.4]non-2-ene-7,9-dione

In the title compound, C23H28N2O 5, the 4,5-dihydro-isoxazole ring adopts a slight envelope conformation and the dioxolane ring is in a twisted conformation. The mol-ecular structure, in the vicinity of the benzyl group, may be influenced by an intra-molecular C- H⋯O hydrogen bond which generates an...

Full description

Bibliographic Details
Published in:	Acta Crystallographica Section E: Structure Reports Online
Main Author:	Bathich Y.; Shaameri Z.; Hamzah A.S.; Quah C.K.; Fun H.-K.
Format:	Article
Language:	English
Published:	2009
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-70449379659&doi=10.1107%2fS1600536809044675&partnerID=40&md5=ffcace3f89327e3e544389cbe1397079

Similar Items

AC Susceptibility and Electrical Properties of PbS added Bi1.6Pb0.4Sr2CaCu2O8 Superconductor; [Kerentanan Arus Ulang Alik dan Sifat Elektrik Superkonduktor Bi1.6Pb0.4Sr2CaCu2O8 dengan Penambahan PbS]
by: Masnita M.J.; Awang R.; Abd-Shukor R.
Published: (2022)

Design, synthesis and therapeutic potential of some 6, 6'-(1,4- phenylene)bis(4-(4-bromophenyl)pyrimidin-2-amine)analogues
by: Kumar S.; Narasimhan B.; Lim S.M.; Ramasamy K.; Mani V.; Shah S.A.A.
Published: (2019)

Effect of Sintering Temperature on AC Susceptibility and Superconducting Properties of (Bi1.6Pb0.4)Sr2CaCu2O8 Superconductor
by: Yusof N.M.; Bakar I.P.A.; Suib N.R.M.; Shukor R.A.; Mujaini M.; Abdullah H.; Humaidi S.; Azman N.J.
Published: (2024)

Impact of SnF2 Addition on AC Susceptibility and Electrical Properties of Bi1.6Pb0.4Sr2CaCu2O8 Superconductor
by: Yusof N.M.; Bakar I.P.A.; Suib N.R.M.; Mujaini M.; Shukor R.A.; Jusoh M.M.; Abdullah H.; Azman N.J.
Published: (2024)

Bis{2-[(E)-(4-fluorobenzyl)iminomethyl]-6-methoxyphenolato- κ 2 N,O 1}nickel(II)
by: Bahron H.; Tajuddin A.M.; Ibrahim W.N.W.; Hemamalini M.; Fun H.-K.
Published: (2011)

(E)-2-Methoxy-N'-(2,4,6-trihydroxybenzylidene)benzohydrazide
by: Taha M.; Baharudin M.S.; Ismail N.H.; Shah S.A.A.; Yousuf S.
Published: (2013)

Synthesis of novel N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-{[5-(un/substituted-phenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetamides as potent antibacterial agents
by: Abbasi M.A.; Irshad M.; Aziz-Ur-Rehman; Siddiqui S.Z.; Shah S.A.A.; Shahid M.
Published: (2022)

Synthesis of some new N-substituted-N-(2,3-Dihydro-[1,4]benzodioxin-6-yl)-4-acetamidobenzenesulfonamides as valuable antibacterial agents
by: Abbasi M.A.; Tariq S.; Aziz-Ur-Rehman; Siddiqui S.Z.; Ahmad I.; Malik R.; Shah S.A.A.
Published: (2016)

Dataset of spectroscopic, crystallography and DFT of novel 1,2-bis[N,N’-6-(4-pyridylmethylamido)pyridyl-2-carboxyamido]butane
by: Kadir M.A.; Haris N.S.H.; Yusof M.S.M.; Kassim K.; Abdul Razak F.I.
Published: (2023)

Synthesis, molecular docking and α-glucosidase inhibition of 5-aryl-2-(6′-nitrobenzofuran-2′-yl)-1,3,4-oxadiazoles
by: Taha M.; Ismail N.H.; Imran S.; Wadood A.; Rahim F.; Saad S.M.; Khan K.M.; Nasir A.
Published: (2016)

4-[5-(2-methoxyphenyl)-1,3,4-oxadiazol-2-yl]benzohydrazide
by: Taha M.; Ismail N.H.; Imran S.; Khan K.M.
Published: (2014)

Synthesis of promising antibacterial and antifungal agents: 2-[[(4-Chlorophenyl)sulfonyl](2,3-dihydro-1,4-benzodioxin-6-yl)amino]-N(un/substituted-phenyl)acetamides
by: Abbasi M.A.; Irshad M.; Aziz-Ur-Rehman; Siddiqui S.Z.; Nazir M.; Ali Shah S.A.; Shahid M.
Published: (2020)

Synthesis, Bacterial biofilm inhibition and cytotoxicity of new N-Alkyl/aralkyl-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-nitrobenzenesulfonamides
by: Abbasi M.A.; Zeb A.; Aziz-Ur-Rehman; Siddiqui S.Z.; Ali Shah S.A.; Shahid M.; Fatima H.
Published: (2020)

Differential gene expression of blood-based ABCA9, CNOT8, SESN1, UCP3, MAP2K1 and DDIT4 in Alzheimer’s disease
by: Samsudin A.Z.; Ramasamy K.; Lim S.M.; Chin A.V.; Tan M.P.; Kamaruzzaman S.B.; Ibrahim B.; Majeed A.B.A.
Published: (2023)

The effects of fe-doping on mechanical properties in Bi1.6Pb0.4Sr2Ca2Cu3-xFexOy superconductor; [Kesan dop ferum terhadap sifat superkonduktor Bi1.6Pb0.4Sr2Ca2Cu3-xFexOy ]
by: Ali S.M.; Hashim A.; Senawi S.A.; Kasim A.; Razali W.A.W.; Mohamed R.; Lothfy F.A.
Published: (2018)

Effect of Yb substitution in Bi1.6Pb0.4Sr2Ca2-xYbxCu3Oy superconductor
by: Hawa J.S.; Azhan H.; Yahya S.Y.S.; Azman K.; Hidayah H.N.; Norazidah A.W.
Published: (2013)

A green and efficient synthetic methodology towards the synthesis of 1-allyl-6-chloro-4-oxo-1,4-dihydroquinoline-3-carboxamide derivatives
by: Gill M.S.A.; Azzman N.; Hassan S.S.; Shah S.A.A.; Ahemad N.
Published: (2022)

Synthesis of new 2-{2,3-dihydro-1,4-benzodioxin-6-yl[(4‑methylphenyl) sulfonyl]amino}-N-(un/substituted-phenyl) acetamides as α-glucosidase and acetylcholinesterase inhibitors and their in silico study
by: Abbasi M.A.; Riaz S.; Aziz-Ur-rehman; Siddiqui S.Z.; Shah S.A.A.; Ashraf M.; Lodhi M.A.; Khan F.A.
Published: (2019)

Bacterial Biofilm Inhibition, Hemolytic Activity, and Structure–Activity Relationship of N-(2,3-Dihydro-1,4-Benzodioxin-6-yl)-4-Nitro-N-(Substituted-Benzyl)benzenesulfonamides
by: Muhammad A. Abbasi; Irshad M.; Aziz-ur-Rehman; Siddiqui S.Z.; Shah S.A.A.; Shahid M.
Published: (2020)

Design, synthesis and biological potential of 5-(2-amino-6-(3/4-bromophenyl)pyrimidin-4-yl)benzene-1,3-diol scaffolds as promising antimicrobial and anticancer agents
by: Kumar S.; Narasimhan B.; Lim S.M.; Ramasamy K.; Mani V.; Ali Shah S.A.
Published: (2019)

Effects of pebax coating concentrations on CO2/CH4 separation of RGO/ZIF-8 PES membranes
by: Jamil N.; Othman N.H.; Shahrudin M.Z.; Razlan M.R.M.; Alias N.H.; Marpani F.; Jye L.W.; Goh P.S.; Ismail A.F.
Published: (2020)

Inhibition of angiogenesis and metastasis in colorectal cancer cell lines through KRAS-associated signaling pathways by 2-methoxy-6-undecyl-1,4-benzoquinone
by: Abd Rahman N.I.; Tham C.L.; Abd Hamid R.
Published: (2024)

Synthesis and α-glucosidase inhibition activity of 2-[3-(Benzoyl/4-bromobenzoyl)-4-hydroxy-1,1-dioxido-2h-benzo[e][1,2]thiazin-2-yl]-n-arylacetamides: An in silico and biochemical approach
by: Saddique F.A.; Aslam S.; Ahmad M.; Ashfaq U.A.; Muddassar M.; Sultan S.; Taj S.; Hussain M.; Lee D.S.; Zaki M.E.A.
Published: (2021)

Ethyl (2RS,3SR,4RS)-1-ethyl-2-(furan-2-yl)-4-hydroxy-5-oxopyrrolidine-3-carboxylate
by: Mohd Rosli N.H.; Mohammat M.F.; Abdul Manan M.A.F.; Cordes D.B.; McKay A.P.
Published: (2024)

4-Fluorobenzyl (Z)-2-(2-oxoindolin-3-ylidene) hydrazine-1-carbodithioate
by: Manan M.A.F.A.; Cordes D.B.; McKay A.P.
Published: (2024)

Synthesis and structural analysis of persuasive antibacterial agents and enzyme inhibitors derived from 5-(1-(4-Tosyl)piperidin-4-yl)-1,3,4-oxadiazol-2-thiol
by: Aziz-Ur-Rehman; Sattar A.; Abbasi M.A.; Siddiqui S.Z.; Raza M.A.; Ashraf M.; Nazir M.; Shah S.A.A.
Published: (2018)

Biological activity of synthesized 5-{1-[(4-chlorophenyl)sulfonyl]piperidin-4-yl}-2-mercapto-1,3,4-oxadiazole derivatives demonstrated by in silico and bsa binding studies
by: Iqbal J.; Ur-Rehman A.; Abbasi M.A.; Siddiqui S.Z.; Rasool S.; Ashraf M.; Iqbal A.; Hamid S.; Chohan T.A.; Khalid H.; Laulloo S.J.; Shah S.A.A.
Published: (2020)

Synthesis, spectral analysis and pharmacological study of N’-substituted-2-(5-((2,4-dimethylphenoxy)methyl)-1,3,4-oxadiazol-2-ylthio)acetohydrazides
by: Rasool S.; Aziz-ur-Rehman; Abbasi M.A.; Siddiqui S.Z.; Shah S.A.A.
Published: (2016)

Genetic polymorphism of CYP2C8 in three Malaysian ethnics: CYP2C8*2 and CYP2C8*3 are found in Malaysian Indians
by: Muthiah Y.D.; Lee W.L.; Teh L.K.; Ong C.E.; Ismail R.
Published: (2005)

Optimization of CTLA-4 and PD-1 proteins in EMT6 Mouse Mammary Cancer Cells by Western Blot
by: Sham N.F.R.; Hasani N.A.H.; Idorus M.Y.; Karim M.K.A.; Fuad S.B.S.A.; Hasbullah H.H.; Ibahim M.J.
Published: (2023)

5,8-Dihydroxy-2,2-dimethyl-12-(3-methylbut-2-enyl)pyrano[3,2-b]xanthen-6-one (brasixanthone B)
by: Binti Seruji N.M.U.; Rosli M.M.; Jong V.Y.M.; Karunakaran T.; Lizazman M.A.; Marlina A.; Binti Halid Y.Y.
Published: (2023)

Synthesis of 6-chloro-2-Aryl-1H-imidazo[4,5-b]pyridine derivatives: Antidiabetic, antioxidant, β-glucuronidase inhibiton and their molecular docking studies
by: Taha M.; Ismail N.H.; Imran S.; Rashwan H.; Jamil W.; Ali S.; Kashif S.M.; Rahim F.; Salar U.; Khan K.M.
Published: (2016)

In-Situ catalytic surface modification of micro-structured La0.6Sr0.4Co0.2Fe0.8O3-δ (LSCF) Oxygen Permeable Membrane Using Vacuum-Assisted technique
by: Othman N.H.; Shahruddin M.Z.; Sihar A.S.; Wu Z.; Li K.
Published: (2016)

Design, synthesis of triazole-based scaffolds, N-(substitutedphenyl)-2-(5-(4-methoxyphenyl)-4-phenyl-4H-1,2,4-triazol-3-ylthiol)acetamides: As potential anti-cholinesterase agents for neurodegenerative diseases
by: Siddiqui S.Z.; Arfan M.; Abbasi M.A.; Aziz-ur-Rehman; Shah S.A.A.; Parveen R.; Ashraf M.; Solangi M.; Hussain S.; Khan K.M.
Published: (2023)

Structure–activity relationship and in silico study of unique bi-heterocycles: 5-[(2-amino-1,3-thiazol-4-yl)methyl]-1,3,4-oxadiazole-2-thiol derivatives
by: Abbasi M.A.; Ramzan M.S.; Aziz-Ur-Rehman; Siddiqui S.Z.; Hassan M.; Raza H.; Shah S.A.A.; Mirza B.; Seo S.-Y.
Published: (2019)

Synthesis, crystal structure and Hirshfeld surface analysis of ethyl 4-hydroxy-2-(4-hydroxyphenyl)-1-methyl-5-oxo-2,5-dihydro1H-pyrrole-3-carboxylate
by: Rashid, et al.
Published: (2023)

Synthesis of 2-{[5-(aralkyl/aryl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(4-methyl-1,3-thiazol-2-yl)acetamides: Novel bi-heterocycles as potential therapeutic agents
by: Ramzan M.S.; Abbasi M.A.; Aziz-Ur-Rehman; Siddiqui S.Z.; Shah S.A.A.; Ashraf M.; Lodhi M.A.; Khan F.A.; Mirza B.
Published: (2018)

Synthesis and corrosion inhibition studies of N-((4 and 3-chlorophenyl) carbamothioyl) benzamide in 1M H2SO4
by: Zulkifli N.Z.; Kassim K.; Nordin N.A.
Published: (2017)

Crystal structure of ethyl 1-(2-hydroxyethyl)-4-((4-methoxyphenyl)amino)-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylate, C16H20N2O5
by: Abdul Rashid F.N.A.; Bacho M.Z.; Slawin A.M.Z.; Abdul Manan M.A.F.; Johari S.A.; Mohammat M.F.
Published: (2023)

Synthesis of Novel Bi-Heterocycles as Valuable Anti-Diabetic Agents: 2-({5-((2-Amino-1,3-Thiazol-4-yl)methyl)-1,3,4-Oxadiazol-2-yl}sulfanyl)-N-(Substituted)acetamides
by: Muhammad Athar Abbasi; Ramzan M.S.; Aziz-ur-Rehman; Siddiqui S.Z.; Shah S.A.A.; Lodhi M.A.; Khan F.A.; Mirza B.
Published: (2020)

Cannot write session to /tmp/vufind_sessions/sess_9s3q2u6ukessjud9f03rrkoc5e