Predicting drug contents of hydroxypropylmethylcellulose films using artificial neural network

The aim of this study is to investigate Artificial Neural Network (ANN) for prediction of drug contents. Hydroxypropylmethylcellulose and loratadine specifically were selected as model matrix polymer and drug. All 0, 5, 10, 20 and 40 mg drug loaded in hydroxypropylmethylcellulose films were conditio...

全面介绍

书目详细资料
发表在:Proceedings of 2009 5th International Colloquium on Signal Processing and Its Applications, CSPA 2009
主要作者: Alias A.; Taib M.N.; Wui W.T.; Anuar N.K.; Tahir N.Md.
格式: Conference paper
语言:English
出版: 2009
在线阅读:https://www.scopus.com/inward/record.uri?eid=2-s2.0-70349929317&doi=10.1109%2fCSPA.2009.5069246&partnerID=40&md5=7cb560146e37806169d4e0c6fab1619e
实物特征
总结:The aim of this study is to investigate Artificial Neural Network (ANN) for prediction of drug contents. Hydroxypropylmethylcellulose and loratadine specifically were selected as model matrix polymer and drug. All 0, 5, 10, 20 and 40 mg drug loaded in hydroxypropylmethylcellulose films were conditioned at the relative humidity of 25, 50 and 75% each prior to psysicochemical characterization using microwave nondestructive testing (NDT) technique. Forward reflection coefficient magnitude S11 produced by microwave NDT technique along with the relative humidity were utilized as inputs to the ANN model with the value of drug contents as output. Initial results showed that an accuracy of 86% is achieved using ANN for prediction of drug contents. ©2009 IEEE.
ISSN:
DOI:10.1109/CSPA.2009.5069246