Factorial design approach to microwave dissolution

• Published in: The Analyst
• Main Author: Mohd A.A.; Dean J.R.; Tomlinson W.R.
• Format: Article
• Language: English
• Published: 1992
• Online Access: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0006349554&doi=10.1039%2fan9921701743&partnerID=40&md5=c26bc5ffc5bd1a863a473b3c90d70643

A fractional factorial design has been used to explore the variables that affect microwave dissolution using perfluoroalkoxy (PFA)-Teflon digestion vessels. Optimum operating conditions for National Research Council of Canada, certified reference material TORT-1 Lobster Hepatopancreas and National Institute of Standards and Technology, Standard Reference Material (SRM) 1575 Pine Needles, were obtained using this procedure. The optimum conditions found for each variable are: 0.25 g sample mass, 6 ml of concentrated hydrochloric acid, 6 ml of concentrated nitric acid, 3 ml of concentrated hydrofluoric acid and 90% microwave power for a total dissolution time of 15 min. Results for Ca, Fe, Cu and Zn in TORT-1 and Ca and Fe in SRM 1575 were in agreement with the certified values.